Is Cymbalta hard on the liver?

Is Cymbalta hard on the liver?

Duloxetine-induced liver injury in patients with preexisting liver disease or chronic alcohol use is known. However, we have found that duloxetine can also induce liver injury in cases without those risk factors. We recommend that clinicians should monitor liver function carefully following duloxetine treatment.

Can you lose weight on Cymbalta?

Conclusion: Duloxetine-treated patients experienced weight loss after short-term treatment, followed by modest weight gain on longer-term treatment. The size of the weight changes observed suggests that the antidepressant duloxetine has minimal effects on weight for the majority of patients.

What happens when you mix Cymbalta and alcohol?

Both alcohol and Cymbalta can lead to liver damage. Taking these two substances together can heighten this risk. Your liver breaks down the substances you consume and removes toxins from your body. Because alcohol contains a number of toxins, chronic use can eventually overwork your liver and lead to liver damage.

How much alcohol is safe with Cymbalta?

Can I drink alcohol whilst taking duloxetine? Drinking alcohol may make you more drowsy, restrict alcohol intake to 1-2 units per day (1 unit=1/2 pint beer or lager, small glass wine or measure of spirit). Consider avoiding alcohol if drowsiness is a particular issue for you.

Is 60 mg of DULoxetine a lot?

nerve pain – the starting dose is 60mg a day and can be increased to 60mg twice a day.

Is 180 mg of Cymbalta too much?

Though the safety of duloxetine above 120mg/day has not been adequately evaluated,14 research indicates that 180mg/day duloxetine is safe for patient cardiac health.

Can duloxetine cause heart palpitations?

A meta- analysis of forty-two placebo-controlled trials on individuals treated with Duloxetine showed a statistically significant increase in palpitations, tachycardia and hypertension [21].